Question

What would be the influence of the genetic mutation that adds a nucleotide to a protein-coding sequence of DNA creating an early stop codon on the resulting protein?

• A. The primary structure of the protein will be unaffected
• B. The secondary structure of the protein will be unchanged
• C. The protein will not be translated at all
• D. The protein will be complete but function abnormally
• E. The protein will be synthesized normally up to the mutation

Answer 1

The correct option is E The protein will be synthesized normally up to the mutation

A mutation introducing stop codon results in translation of truncated protein. So, the protein will be translated normally till mutated site and the synthesis will be terminated prematurely. Synthesis of truncated protein would affect the primary and secondary structure of protein. Thus, the correct answer is option E.