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Question

When one molecule of pyruvic acid undergoes krebs cycle, how many CO2 molecules are formed?

A
6 CO2
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B
3 CO2
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C
No CO2 formed
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D
2 CO2
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Solution

The correct option is B 3 CO2
Three CO2 molecules are formed. One CO2 is formed during oxidative decarboxylation of pyruvic acid. Two CO2 molecules are formed in krebs cycle, one during the conversion of 6-carbon oxalosuccinate to 5-carbon α-ketoglutarate and the other during the conversion of α-ketoglutarate to 4-carbon succinyl CoA.

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