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Question

When the portion of the aspartate transaminase enzyme from different species are sequenced. The amino acid sequences are shown in the table. Each letter stands for an amino acid. Differences from the human sequence are indicated by bold letters. Missing amino acids are indicated by a dash (-).
Which of the following mutations could not resulted in the amino acid differences?

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A
a deletion
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B
an insertion
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C
a missense mutation
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D
a silent mutation
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E
a substitution
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Solution

The correct option is D a silent mutation
A mutation causing the no change in the amino acid and hence no effect on the function of the protein is called as silent mutation; if point mutation alters the third base of the codon, there is no change in amino acid. Thus, the correct answer is option D.

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