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B
When fertilized ovum takes place.
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C
During sexual intercourse.
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D
During fission of unfertilized egg.
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Solution
The correct option is A During fertilization. Chromosomal sex determination is carried out at fertilization. This is done based on the presence or absence of the Y chromosome. Either the X or Y chromosome from the sperm fuses with the X chromosome of the egg and so females have XX and males have XY.