The correct option is B Pyrogen
Pyrogens are chemicals that induce fever. They have an effect on the thermoregulatory centre in the hypothalamus. They suppress heat-sensing neurons while stimulating cold-sensing neurons, causing the hypothalamus to raise body temperature above normal levels. As a result, a condition known as fever develops. Pyogen's activity, which causes a febrile response, is thought to be part of the body's ability to fight infection. Infectious microorganisms that cannot sustain a larger temperature range may be killed or inhibited by a rise in body temperature. The increase in body temperature may also aid in the stimulation of white blood cell motility, activity, and multiplication, as well as the creation of antibodies.