Question

Where are Nissl’s granules found and what is their nature?

Answer 1

Nissl's granules granules that occur in the cell bodies ofneurones.They are formed of a nucleoprotein combined with iron and are concerned with protein synthesis.

Nissl bodies can be demonstrated by a method of selective staining developed by Nissl (Nissl staining), using an anilinestain to label extranuclearRNAgranules. This staining method is useful to localize the cell body, as it can be seen in thesomaanddendritesof neurons, though not in theaxonoraxon hillokDue to RNA's basophillic("base-loving") properties it is stained blue by this method.

Nissl bodies show changes under various physiological conditions and inpathological lconditionsthey may dissolve and disappear.