The correct option is D Upstream of transcription sites
The gene that codes for any RNA/protein product which does not serve as regulatory protein is known as structural genes. The operator is a DNA sequence present between the promoter region and the first coding gene. The operator region serves as the repressor protein binding site. The promoter is a DNA segment that serves to initiate transcription of a particular gene. They are present upstream near the transcription start sites of genes in between the operator and structural gene. The regulatory gene regulates the expression of structural genes by its protein products that are mostly transcription factors. It is not the part of an operon, which means that it is present upstream or downstream the structural genes but not in between; the Regulatory gene is present upstream the operator gene. Thus, the correct answer option D.