The correct option is B 2x+1
x2+x6−16
=6x2+x−16
=16(6x2+x−1)
Now, we will factorise the polynomial by splitting its middle term.
16(6x2+x−1)
=16(6x2+3x−2x−1)
=16(3x(2x+1)−1(2x+1))
=16(3x−1)(2x+1)
Therefore, 16,(3x−1) and (2x+1) are factors of x2+x6−16.