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Question

Which among the following is not involved in the muscular contraction?

A
Ca ion
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B
Troponin
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C
Actin
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D
Mg ion
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Solution

The correct option is A Mg ion
  • Active sites for myosin(Thick filament) are present on actin which are masked by troponin in resting state. when Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
  • Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge.
  • This pulls the attached actin filaments towards the centre of ‘A’ band.
  • The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
  • magnesium acts as a natural calcium blocker to help muscles relax. Hence Mg ion is not involved in the muscular contraction but it is involved in muscle relaxation by blocking calcium ions.
  • So, the correct answer is 'Mg'

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