Question

Which among the following secretions of the Sertoli cells helps in the regression of the development of female accessory ducts in male?
1. Androgen binding protein
2. Inhibin
3. Anti-mullerian hormone

• A. 1 only
  
• B. 1 and 2 only
• C. 2 and 3 only
• D. 3 only

Answer 1

The correct option is D 3 only

Anti-mullerian hormones cause regression of Mullerian ducts in the male embryos which would otherwise develop as oviducts, uterus and upper vagina.
Sertoli cells help in the regulation of spermatogenesis. They act and function as structural and metabolic support of the germ cells, sperm release, secretion of tubular fluids for sperm transport and maintenance of a permeability barrier between interstitial and tubular compartments.
Sertoli cells secrete various proteins, including ABP (Androgen Binding Protein), as well as hormones such as inhibin and anti-mullerian hormone.
Androgen binding protein is a glycoprotein that helps to concentrate testosterone in the seminiferous tubules.
Inhibin is a proteinaceous hormone secreted by Sertoli cells in men and granulosa cells in women, it inhibits the synthesis and release of the follicle-stimulating hormone(FSH).