Which are III and VII factors responsible for blood clotting?

Prothrombin, Calcium

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Thromboplastin, Proaccelerin

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Thromboplastin, Proconvertin

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Prothrombin, Antihaemophilic globulin (AHG)

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Solution

The correct option is B Thromboplastin, Proconvertin
Blood clotting is a process by which a gel-like mass is formed by platelets and fibrin in the blood to stop bleeding. The coagulation cascade involves the series of coagulation factors that helps in the formation of fibrin clot. Factor III is thromboplastin. It is a tissue factor. It requires calcium and factors V, VII, and X to convert prothrombin into thrombin. It is found in the brain, lung, vascular endothelium, liver, placenta and kidneys. Factor VII isproconvertin. It is stable to heat and storage. It accelerates the conversion of prothrombin to thrombin. It is vitamin K-dependent factor and is manufactured in the liver.
Thus, the correct answer is 'Thromboplastin, Proconvertin.'

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