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Question

Which can be observed in an interphase nucleus under the light microscope?

A
Chromosome
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B
Nucleosome
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C
Centromere
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D
Heterochromatin
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Solution

The correct option is D Heterochromatin
In an interphase, nucleus heterochromatin can be seen under the light microscope. The heterochromatin is condensed in the secondary constriction I and II of the chromosome. Heterochromatin is a tightly packed form of DNA, which comes in different varieties. These varieties lie on a continuum between the two extremes of constitutive and facultative heterochromatin. Both play a role in the expression of genes. Chromatin is found in two varieties: euchromatin and heterochromatin. Heterochromatin has been associated with several functions, from gene regulation to the protection of the integrity of chromosomes; some of these roles can be attributed to the dense packing of DNA, which makes it less accessible to protein factors that usually bind DNA or its associated factors.

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