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Question

Which cell type would not be a direct target for gene therapy?

A
Erythrocytes
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B
Muscle fibre
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C
Epithelial cell
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D
Hepatocyte
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Solution

The correct option is A Erythrocytes
Gene therapy is a technique to replace a faulty gene or add a missing gene.
Red blood cells or erythrocytes are enucleated meaning that they lack a cell nucleus. They have no DNA in mature form so are not suitable for gene therapy. Muscle fibre, epithelial cells and hepatocytes possess nucleus and can be used for gene therapy.

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