Question

Which cells of the ovary are involved in the synthesis of estrogen?

• A. Theca interna cells
• B. Granulosa cells
• C. Interstitial cells
• D. Both A and B

Answer 1

Answer: (D)

Both A and B

Theca interna cells have receptors for luteinizing hormone (LH) to produce androstenedione. Androstenedione is an androgen. This androstenedione provides the precursor for estrogen to the granulosa cells. Granulosa cells then convert androgens produced by thecal cells to estradiol during the follicular phase.

Thus, the correct answer is option D.