The correct option is B Acentric chromosome
Acentric chromosomes may be lost during cell division. An acentric fragment is a segment of a chromosome that lacks a centromere. Because the centromere is the point of attachment for the mitotic apparatus, acentric fragments are not evenly distributed to the daughter cells in cell division. As a result, one of the daughters will lack the acentric fragment. Lack of the acentric fragment in one of the daughter cells may have deleterious consequences, depending on the function of the DNA in this region of the chromosome