wiz-icon
MyQuestionIcon
MyQuestionIcon
15
You visited us 15 times! Enjoying our articles? Unlock Full Access!
Question

Which disease in children is caused by intensive use of nitrate fertiliser?

A
Jaundice
No worries! We‘ve got your back. Try BYJU‘S free classes today!
B
Methemoglobinemia
Right on! Give the BNAT exam to get a 100% scholarship for BYJUS courses
C
Mumps
No worries! We‘ve got your back. Try BYJU‘S free classes today!
D
Septicemia
No worries! We‘ve got your back. Try BYJU‘S free classes today!
Open in App
Solution

The correct option is B Methemoglobinemia
Methemoglobinemia is a disorder caused by the presence of a higher than normal level of methemoglobin (metHb, i.e., ferric [Fe3+] rather than ferrous [Fe2+] haemoglobin) in the blood. Methemoglobin is a form of hemoglobin that contains ferric [Fe3+] iron and has a lesser affinity for oxygen. However, the ferric iron has an increased affinity for bound oxygen. The binding of oxygen to methemoglobin results in an increased affinity of oxygen to the three other heme sites (that are still ferrous) within the same tetrameric hemoglobin unit. This leads to an overall reduced ability of the red blood cell to release oxygen to tissues, with the associated oxygenhemoglobin dissociation curve, therefore, shifted to the left. When methemoglobin concentration is elevated in red blood cells, tissue hypoxia can occur.
So, the correct answer is option B.

flag
Suggest Corrections
thumbs-up
0
Join BYJU'S Learning Program
similar_icon
Related Videos
thumbnail
lock
Biotechnology and Its Application
BIOLOGY
Watch in App
Join BYJU'S Learning Program
CrossIcon