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Question

Which enzyme is responsible for the conversion of inactive fibrinogens to fibrin?

A
Thrombokinase
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B
Thrombin
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C
Renin
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D
Epinephrine
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Solution

The correct option is B Thrombin
Blood coagulation is a mechanism to prevent excessive loss of blood from the body. Whenever there is an injury, a cascade of different proteins called clotting factors are activated to form blood clots.

Thrombokinase is an enzyme complex liberated from the damaged tissues and blood platelets. It converts prothrombin to thrombin.

Thrombin further catalyzes the polymerization of soluble fibrinogen into insoluble fibrin threads. Fibrin forms an insoluble mesh, in which blood cells are trapped to form a clot.

Renin hormone secreted from the kidney controls blood pressure.

Epinephrine hormone is secreted by the adrenal medulla. It is also called adrenaline. It is produced in response to stress and increases heart rate, strengthens the force of the heart’s contraction and cardiac output.

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