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Question

Which enzyme/s will be produced in a cell in which there is a non-sense mutation in the lac y gene?

A
Lactose permease
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B
Transacetylase
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C
Lactose permease and transacetylase
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D
β-galactosidase
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Solution

The correct option is D β-galactosidase
An operon is a coordinated group of genes that act as a single regulatory unit.

The lac operon has three structural genes (lac z, lac y and lac a), an operator region (o), promoter region (p) and regulatory gene (i).


z gene codes for β-galactosidase – responsible for the hydrolysis of the disaccharide, lactose into its monomeric units, galactose and glucose.

y gene codes for permease - increases permeability of lactose.

a gene codes for transacetylase - plays an important role in lactose utilization.

A type of mutation in which the resulting codon is a stop codon is called nonsense mutation and hence transcription stops from that point.


So, the correct answer is option A.

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