Question

Which halide ion is the best nucleophilie in dimethyl sulfoxide solution?

• A. Fluoride
• B. Chloride
• C. Bromide
• D. Iodide

Answer 1

The correct option is A Fluoride

In polar aprotic solvent like $DMSO,DMF,CHC{l}_3$, there is no hydrogen bond formation and nucleophilicity order is same as the basicity order of halides.

$F^{-}>C{l}^{-}>B{r}^{-}>I^{-}$

$\therefore F^{-}$ is the best nucleophile in the polar aprotic solvent like dimethyl sulfoxide solution.