Question

Which is susceptible to feedback inhibition?

• A. Zymogen
• B. Zymase
• C. Diastase
• D. Hexokinase

Answer 1

The correct option is D Hexokinase

Feedback inhibition is the process by where the end product terminates the reaction. The accumulation of the end product interferes with the enzymatic activity by changing the shape of its active sites, on changing the shape of the active site, the substrate does not attach to the active site and thus the reaction terminates. During glycolysis, the glucose changes to glucose 6-phosphate in presence of hexokinase. When the amount of glucose and phosphate exceeds it deactivate hexokinase.

Hence the correct answer is (D).