Question

Which is the best HLA (human leucocyte antigen) match for transplant in order of preference?

• A. Parent > sibling > twin > unrelated donor
• B. Sibling > twin > parent > unrelated donor
• C. Twin > sibling > parent > unrelated donor
• D. Twin > unrelated donor > parent > sibling
• E. Sibling > parent > twin > unrelated donor

Answer 1

Answer: (C)

Twin > sibling > parent > unrelated donor

Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants. HLA are proteins found on most cells in your body which acts like markers in our immune system to recognize which cells belong in your body and which do not. A close match is important because it Improves the chances for a successful transplant.

So, the preference order is Twin >sibling >parent >unrelated donor.