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Question

Which is the Claisen condensation product of ethyl propanoate ?

A
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B
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C
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D
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Solution

The correct option is A

Ester undergoes self condensation in presence of strong base to give β-ketoester. This reaction is called Claisen condensation reaction.



Mechanism of Claisen condensation reaction:
1. Enolate formation : The strong base will abstract the acidic α-hydrogen to form the enolate ion.

2. Nucleophile attack: Formed enolate will attack the carbonyl carbon of another ester molecule and leaving group (-OR) will leave the compound to form β ketoester.

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