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Question

Which is the hexose molecule that is acted upon by aldolase and broken down into two triose molecules during glycolysis?

A
Glucose
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B
Fructose
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C
Glucose-6-phosphate
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D
Fructose-1,6-bisphosphate
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Solution

The correct option is D Fructose-1,6-bisphosphate
The pathway of the breakdown of glucose into pyruvic acid is termed as glycolysis. This pathway is a step-wise process in which glucose (a hexose) is broken down into two pyruvate molecules (triose) via a series of reactions involving several intermediate compounds. The substrate for aldolase enzyme is fructose-1,6-bisphosphate (hexose). The enzyme aldolase converts fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate, which are triose sugars and isomers of each other.


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