Question

Which is worse point or frameshift mutations?

Answer 1

Mutation:

1. The mutation is an instant change in the structure of genes due to a nucleotide change.
2. Two different forms of gene mutations are point mutation and frameshift mutation.
3. Mutations can be brought on by mistakes in DNA replication and because of mutagens.
4. Gene mutations, which affect a gene's nucleotide sequence, are minor changes.

Comparison between the types of mutations:

1. In a frameshift mutation, the entire reading frame of the codon is changed, and thus a new polypeptide is formed.
2. Point mutations are changes that take place at a single nucleotide.
3. The intensity of the effects from point mutations in genes depends on what occurs in the encoded amino acid sequence.
4. In comparison to point mutations, frameshift mutations are often far more severe and frequently more fatal as it changes the reading frame.
5. Point mutations only impact one nitrogen base, however in this case the single base is either totally destroyed or an additional one is introduced into the midst of the DNA sequence, despite only affecting one nitrogen base.
6. A frameshift mutation causes Tay-Sachs disease.