Which metal ion is present as cofactor in carboxypeptidase ?
A
Zn++
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B
Mn++
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C
Cl−
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D
Nl
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Solution
The correct option is BZn++ Carboxypeptidase commonly called as CPA plays an important role in the metabolism of protein. It contains zinc ion as cofactor which helps in hydrolyzes of carbon in COOH group present on one of the terminals of amino acids. Loss of this Zn+2 ion will destroy the enzymatic activity of CPA as enzyme commonly follow the lock and key mechanisms which demands unaltered structures.