Which of the following amine will be prepared by Gabriel pthalamide reaction?

n-butyl amine

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Tert- butyl amine

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Neo-pentylamine

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Tri-ethylamine

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Solution

The correct option is A n-butyl amine
Gabriel phthalimide reaction is used to prepare primary unhindered amine only.
Among the above options, n-butyl amine can be prepared by Gabriel phthalimide synthesis.
The reaction is as follows:

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Why cannot aromatic primary amines be prepared by Gabriel phthalimide synthesis?

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