Question

Which of the following amines can be prepared by Gabriel phthalimide reaction?

• A. n - butylamine
• B. Triethylamine
• C. t-butylamine
• D. neo -pentylamine

Answer 1

The correct option is A n - butylamine

n-butylamine $\left(C{H}_{3}C{H}_{2}C{H}_{2}C{H}_{2}N{H}_2\right)$ can be prepared by Gabriel phthalimide reaction. This method produces only primary amines without the traces of secondary or tertiary amines. In this method, phthalimide is treated with ethanolic $KOH$, it forms potassium salt of phthalimide which on heating with alkyl halide followed by alkaline hydrolysis forms corresponding primary amines.
Triethylamine, t-butylamine and neo-pentylamine cannot be prepared by Gabriel phthalimide reaction.