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Question

Which of the following amino acids were not found to be synthesized in Millers’s experiment?

A
Alanine
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B
Glycine
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C
Aspartic acid
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D
Glutamic acid
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Solution

The correct option is D Glutamic acid

In 1953, Stanley Miller and his advisor Harold Urey created experimental conditions similar to the proposed conditions on early earth, by Oparin and Haldane, - high temperature, volcanic storms, reducing atmosphere containing methane, ammonia, hydrogen etc.They used a closed flask containing methane, ammonia, hydrogen (ratio 2:1:2) and passed steam over it by boiling water and connecting it with a glass tube. They needed an energy source to provide the conditions necessary for molecules to overcome their stability and fuse to form different structures. Miller and Urey took two tungsten electrodes and created a discharge between them, which raised the temperatures to almost 80C. In this high-energy chamber, they could synthesize several significant substances including amino acids such as glycine, alanine and aspartic acid. Glutamic acid was not found in their observation.


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