Question

Which of the following applies to Bohr effect?

• A. Effect of CO${}_2$ and H${}^{+}$ on the oxygen affinity of haemoglobin
• B. Partial pressure of O${}_2$ in pulmanory veins
• C. Exchange of chloride and bicarbonate ions between RBC and plasma
• D. Partial pressure of O${}_2$ in systemic arteries

Answer 1

Answer: (A)

Effect of CO${}_2$ and H${}^{+}$ on the oxygen affinity of haemoglobin

The Bohr effect refers to the observation that increases in the carbon dioxide partial pressure of blood or decreases in blood pH result in a lower affinity of hemoglobin for oxygen. This manifests as a right-ward shift in the oxygen-hemoglobin dissociation curve described in oxygen transport and yields enhanced unloading of oxygen by hemoglobin.