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Question

Which of the following are mitotic poisons?

A
Colchicine
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B
Mustard gas and azides
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C
Cyanides
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D
All of the above
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Solution

The correct option is D All of the above
All the options mentioned are mitotic poisons or inhibitors. A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the cell apart when it divides. Mitotic inhibitors are used in cancer treatment, because cancer cells are able to grow and eventually spread through the body (metastasize) through continuous mitotic division and so are more sensitive to inhibition of mitosis than normal cells.

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