Which of the following are needed for blood clotting?
A
Ca++ and vitamin E
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B
Ca++ and vitamin K
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C
K+ and vitamin A
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D
K+ and vitamin K
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Solution
The correct option is C Ca++ and vitamin K
Calcium ion and vitamin K are needed for blood clotting. Coagulation (thrombogenesis) is the process by which blood forms clots. Vitamin K adds a carboxyl group to multiple factors of the coagulation cascade. In adding the gamma-carboxyl group to glutamate residues on the immature clotting factors, Vitamin K is itself oxidized.
Calcium mediates the binding of the complexes to the phospholipid surfaces expressed by platelets.