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Question

Which of the following array of genes can be related to a kidney transplant?

A
MHC
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B
HLA
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C
Lac gene
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D
All of the above
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Solution

The correct option is C HLA
The genes related to kidney transplant rejection are present on p (shorter) and q (longer) arm of chromosome number 6. These genes are polymorphic with 6 pairs of alleles,namely, HLA-A, HLA-C, HLA-B, HLA-DP, HLA -DR and HLA-DQ. These genes present antigen which are identified as self and non-self by the immune system of the body and those cells or tissues that are identified as foreign by T-lymphocytes are subjected to destruction So, the correct answer is 'HLA'

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