Question

Which of the following biomolecules is common to respiration ­mediated breakdown of fats, carbohydrates and proteins?

• A. Fructose 1, 6-­bisphosphate
• B. Glucose-­6-­phosphate
• C. Acetyl CoA
• D. Pyruvic acid

Answer 1

The correct option is C

Acetyl CoA

The correct option is C.

Explanation of correct option:

1. Acetyl CoA is a frequent step in the breakdown of all biomolecules in the respiratory route.
2. Carbohydrates are turned into glucose initially.
3. The TCA cycle begins with glucose being transformed to pyruvate, which is subsequently decarboxylated to acetyl CoA.
4. The breakdown of fats results in the formation of fatty acids and glycerol. Acetyl CoA is formed from fatty acids.
5. Proteins break down as amino acids, which are deaminated and enter the Krebs cycle as pyruvate or acetyl CoA intermediates.

Explanation of incorrect options:

Option (A):

1. Fructose 1,6-bisphosphate, often known as the Harden-Young ester, is a phosphorylated fructose sugar with carbons 1 and 6 phosphorylated.
2. In cells, the -D form of this molecule is prevalent.

Option (B):

1. Glucose 6-phosphate is a glucose molecule that has had its hydroxy group on carbon 6 phosphorylated.
2. Because the majority of glucose entering a cell is phosphorylated in this way, this dianion is quite prevalent in cells.

Option (D):

1. Pyruvic acid is the 2-keto derivative of propionic acid and is a 2-oxo monocarboxylic acid.
2. It's a metabolite produced by glycolysis.
3. It functions as a cofactor and a fundamental metabolite.
4. It's made out of propionic acid.

Final answer: Acetyl CoA is the biomolecule that is common to respiration ­mediated breakdown of fats, carbohydrates, and proteins.