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Question
Which of the following can cause mutations which contribute to development of cancer?
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Solution
The correct options are
A Chemicals in food
B UV and ionising radiations
D Reactive oxygen species
Carcinogenic (potentially cancer causing) chemicals can be present in some foods. Ionising and uv radiation can both cause DNA damage. Reactive oxygen species which are generated in cells from molecular oxygen can also modify DNA, causing mutations. Cancers are mainly due to mutation.However, there is no evidence that HIV virus introduces mutations into cells. Its contribution to development of cancers is probably that it suppresses the immune response, making immune surveillance less effective.
A Chemicals in food
B UV and ionising radiations
D Reactive oxygen species
Carcinogenic (potentially cancer causing) chemicals can be present in some foods. Ionising and uv radiation can both cause DNA damage. Reactive oxygen species which are generated in cells from molecular oxygen can also modify DNA, causing mutations. Cancers are mainly due to mutation.However, there is no evidence that HIV virus introduces mutations into cells. Its contribution to development of cancers is probably that it suppresses the immune response, making immune surveillance less effective.
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