Which of the following can damage optic nerve leading to blindness, if taken internally?

(a) CH₃COOH
(b) C₂H₅OH
(c) NaHCO₃
(d) CH₃OH

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Solution

(d) CH₃OH
CH₃OH (methanol), when consumed, oxidises into methanal into the liver. This causes coagulation of protoplasm in the cells, as methanal reacts rapidly with the components of the cells. Due to this, the cells stop functioning and damage the optic nerve leading to blindness.

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\begin{matrix} Eye diseases & Defect (1) Glaucoma & (A) an infection in the layer of the eye which causes inflammation (2) Colour blindness & (B) increased pressure in the eye which causes damage to the optic nerve (3) Conjunctivitis & (C) lens of the eye becomes opaque resulting in blindness (4) Cataract & (D) inability to distinguish between colours due to defect in photoreceptors \end{matrix}

In the blind spot, where the optic nerves leave the eyes, ___ .

C H_{3} C H_{2} O H + 2 [O] a l k - ---- \to K M n O_{4} H_{2} O +

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