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Question

Which of the following causes denaturation of proteins?

A
Change in pH
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B
Exposure to heat
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C
Exposure to acid or bases
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D
None of the above
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Solution

The correct options are
A Change in pH
B Exposure to heat
C Exposure to acid or bases
When proteins are subjected to external stress like addition of acids and bases, exposure to heat, or change in pH, the hydrogen bonds in the proteins are deteriorated and helix gets uncoiled, thus losing its biological activity.

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