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Question

Which of the following cell surface differentiation is not likely to play a role in inter-cellular communication?

A
Desmosome
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B
Gap junction
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C
Tight junction
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D
None of the above
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Solution

The correct option is D Tight junction
Gap Junctions are fine hydrophilic channels formed by special protein cylinders or Connexons of two adjacent cells.
Desmosomes are like welded areas between adjacent cells having intercellular thickening materials and connects with the adjacent cell membrane for intercellular communication.
In tight Junctions, plasmalemma of two cells is fused to form an impermeable or occluding junction, e.g., epithelial cells of capillaries and brain cells. As tight junctions are impermeable, they do not play a role in inter-cellular communication.
So, Option C is the correct answer.

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