Question

Which of the following cells play an important role in failure of transplanted organ?

• A. $C{D}_4$ cells and $C{D}_8$ cells
• B. Natural killer cells
• C. Plasma cells
• D. Mast cells

Answer 1

Answer: (A)

$C{D}_4$ cells and $C{D}_8$ cells

Transplant rejection occurs as an immune response of the body mediated by killer T cells( cellular) and activated B cells( humoral). CD4 and CD8 cells play an important role in graft rejection leading to transplant failure by triggering a response to destroy any object that identifies as foreign object to the body.

Thus the answer is option A.