Question

Which of the following cells secrete histamine?

• A. Plasma cells
• B. Mast cells
• C. Monocytes
• D. N.K.cells

Answer 1

The correct option is B Mast cells

• A mast cell is also known as a mastocyte.
• It is a resident cell of connective tissue that contains many granules rich in histamine and heparin. The mast cell is very similar in both appearance and function to the basophil, another type of white blood cell.
• A unique, stimulus-specific set of mast cell mediators is released through degranulation following the activation of cell surface receptors on mast cells.
• Examples of mediators that are released into the extracellular environment during mast cell degranulation include:

serine proteases, such as tryptase and chymase

histamine

serotonin etc.

• Hence, Mast cells secrete histamine.
• So, the correct answer is 'Mast cells'.