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Question

Which of the following chemical is a base analogue ?

A
5-bromouracil
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B
Acridines
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C
Nitrous acid
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D
Hypoxanthine
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Solution

The correct option is A 5-bromouracil

A.5-bromouracil - brominated derivative of uracil that acts as an antimetabolite or base analogue.

B.Acridines - an organic compound and a nitrogen heterocycle with the formula C13H9N. Acridines are substituted derivatives of the parent ring. It is a planar molecule that is structurally related to anthracene with one of the central CH groups replaced by nitrogen.

C.Nitrous acid - a weak and monobasic acid known only in solution and in the form of nitrite (NO − 2. ) salts. Nitrous acid is used to make diazonium salts from amines.

D.Hypoxanthine - a naturally occurring purine derivative. It is occasionally found as a constituent of nucleic acids, where it is present in the anticodon of tRNA in the form of its nucleoside inosine.

So, the correct option is ‘5-bromouracil’.

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