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Question

Which of the following cofactor is responsible for the activity of an enzyme leading to the formation of carbonic acid in RBCs?

A
Ca++
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B
Zn++
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C
Mn++
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D
Mg++
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Solution

The correct option is B Zn++
The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyse the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes.
So, the correct option is 'Zn++'

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