Which of the following compound is resistant to nucleophilic attack of OH− ion?
A
acetamide
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B
acetonitrile
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C
methyl acetate
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D
diethyl ether
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Solution
The correct option is D diethyl ether Acetamide, acetonitrile and methyl acetate contains an unsaturated carbon atom which can be easily attacked by a nucleophile such as hydroxide ion.
Also C=O group in which oxygen is electronegative so carbon electron defecient on which nucleophile can attack.