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Question

Which of the following compounds will be most easily hydrolysed?
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A
Acid halide
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B
Acid amide
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C
Ester
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D
Acid anhydride
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Solution

The correct option is A Acid halide
Acid halide is most easily hydrolysed as halide is a strong leaving group and weak conjugate base. Weaker the basic character of leaving group more is the reactivity of acid derivative.

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