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Question

Which of the following cycles in liver is mainly responsible for the synthesis of urea?

A
Citruline cycle
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B
Krebs cycle
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C
Nitrogen cycle
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D
Ornithine cycle
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Solution

The correct option is D Ornithine cycle
The byproducts of protein metabolism like the ammonia and ammonium salts are toxic for the body. Hence they are converted to urea in the liver by a process known as urea cycle or ornithine cycle. The overall urea formation reaction is: 2 Ammonia + carbon dioxide + 3ATP ---> urea + water + 3 ADP.
So, the correct answer is option D.

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