Which of the following demonstrates the use of immunofluorescence?
A
Identification of viral antigens in various substrates.
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B
Identification & quantification of antibody in sera.
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C
Establishing the pathogenesis of some viral infections.
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D
All of the above.
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Solution
The correct option is D All of the above.
Immunofluorescence has various uses. It helps in identification of viral antigens and antibodies including RSV, flu A, flu B, and adenoviruses, detection of rotavirus antigen in faeces, the detection of HSV and VZV in skin scrappings, and the detection of HBsAg in serum. It also help in identifying the the development of disease in case of some viral infections for e.g., influenza A virus in mice.