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Question
Which of the following disorders is not caused by a mutation in the DNA sequence?
Which of the following disorders is not caused by a mutation in the DNA sequence?
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Solution
The correct option is D AIDS
Sickle cell anaemia is caused by a mutation in Hbb gene, that codes the beta chain, causes replacement of A by T at the 17th nucleotide of the Hbb gene changes the codon GAG (glutamic acid) to GTG (which encodes valine). Phenylketonuria (PKU) is an inborn metabolic error and is caused by defective gene for phenylalanine hydroxylase. Cystic fibrosis is caused by mutation in CFTR gene, present on long (q) arm of chromosome 7, codes for chloride channels. Hemophilia is also X linked recessive disorder caused bymutation in gene of clotting factor. AIDS (acquired immunodeficiency syndrome) is caused by HIV (Human Immunodeficiency Virus) which makes people much more vulnerable to infections and diseases. Hemophilia is caused by genetic mutation, where the blood doesn't clot normally.Correct answer is D.
Sickle cell anaemia is caused by a mutation in Hbb gene, that codes the beta chain, causes replacement of A by T at the 17th nucleotide of the Hbb gene changes the codon GAG (glutamic acid) to GTG (which encodes valine).
Phenylketonuria (PKU) is an inborn metabolic error and is caused by defective gene for phenylalanine hydroxylase.
Cystic fibrosis is caused by mutation in CFTR gene, present on long (q) arm of chromosome 7, codes for chloride channels. Hemophilia is also X linked recessive disorder caused by
mutation in gene of clotting factor.
AIDS (acquired immunodeficiency syndrome) is caused by HIV (Human Immunodeficiency Virus) which makes people much more vulnerable to infections and diseases.
Hemophilia is caused by genetic mutation, where the blood doesn't clot normally.
Correct answer is D.
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