Which of the following displays immunosuppressant?
A
B-cells
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B
α-cells
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C
T-cells
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D
Both (1) & (3)
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Solution
The correct option is A Both (1) & (3) The body's immune system is a normally occurring protective mechanism that helps the body defend itself against harmful agents. However, sometimes the immune system perceives normally harmless substances such as allergens or the person's own body tissues as harmful invaders and try to eliminate them. This inappropriate activation of the immune response is a major factor in allergic and auto-immune disorders. Immunosuppressants are the drugs that suppress the immune to reduce the risk of rejection of foreign bodies with organ transplants or in auto-immune disorders. B-cells are lymphocytes capable of producing antibodies and can capture circulating antigens. They are produced from stem cells in the bone marrow of adult mammals, liver of foetus and bursa of Fabricius in birds. The mature B-cells synthesize various types of antibodies which are displayed on their membrane surfaces, hence they are called immuno-competent B-cells. They are the cause of Humoral immunity. T-cells are the lymphocytes that can recognize antigens if presented by antigen-presenting cells (APCs) by MHC molecules. They are the cause of cell-mediated immunity. Therefore, both B-cells and T-cells reveal the immunosuppressants on their surface and are part of the immune system. Alpha cells are one of the types of cells in the Islets of Langerhans in the endocrine portion of the pancreas, which produces the hormone glucagon that is secreted in response to hypoglycemia.