Which of the following enzyme helps in conversion of 6-phosphogluconate to ribulose-5-phosphate?

6-phosphogluconate dehydrogenase

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Hexokinase

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Alpha-ketoglutarate

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None of the above

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Solution

The correct option is A 6-phosphogluconate dehydrogenase
This conversion takes place during the oxidative phase of the pentose phosphate pathway.
Here, When 6-phosphogluconate converts to ribose 5-phosphate, the enzyme used is 6-phosphogluconate dehydrogenase.
In this step an NADP⁺ converts to NADPH and CO₂ is released.
So, the correct option is '6-phosphogluconate dehydrogenase.'

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