Which of the following ETS complex is inhibited by cyanide?
A
Complex II
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B
Complex V
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C
Complex IV
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D
Complex III
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Solution
The correct option is C Complex IV Some poisons, including cyanide, inhibit the normal activity of the cytochromes. Cyanide binds tightly to the iron in the last cytochrome in the electron transport chain (cytochrome a3- component of complex IV), making it unable to transport electrons to oxygen. This blocks the further passage of electrons through the chain and ATP production ceases.