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Question
Which of the following factors does not induce left shift (dotted lines) as shown in the following graph?
Which of the following factors does not induce left shift (dotted lines) as shown in the following graph?
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Solution
The correct option is A Decreased pH
The graph represents the oxygen-dissociation curve. The factors that shift the curve to the left would be decreased pCO2, decreased H+ ion concentration (which means increased pH), decreased temperature, decreased concentration of 2,3-bisphosphoglycerate. Higher pCO2 results in higher [H+] due to the formation of carbonic acid. This lowers the pH of the blood, shifting the curve to the right. Lower pCO2 leads to lower [H+], increasing the blood pH. This shifts the curve to the left. Thus, option A is wrong, as decreased pH would shift the curve to the right.
Decreased pH
The graph represents the oxygen-dissociation curve. The factors that shift the curve to the left would be decreased pCO2, decreased H+ ion concentration (which means increased pH), decreased temperature, decreased concentration of 2,3-bisphosphoglycerate. Higher pCO2 results in higher [H+] due to the formation of carbonic acid. This lowers the pH of the blood, shifting the curve to the right. Lower pCO2 leads to lower [H+], increasing the blood pH. This shifts the curve to the left. Thus, option A is wrong, as decreased pH would shift the curve to the right.
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